Recombinant Dna Technology and Biotechnology

RECOMBINANT DNA TECHNOLOGY AND BIOTECHNOLOGY Introduction to Biotechnology and Recombinant DNATechnology

Soluble Expression of Recombinant Nerve Growth Factor in Cytoplasm of Escherichia coli

Background: Pivotal roles of Nerve growth factor (NGF) in the development and survival of both neuronal and non-neuronal cells indicate its potential for the treatment of neurodegenerative diseases. However, investigation of NGF deficits in different diseases requires the availability of properly folded human b-NGF. In previous studies bacterial expression of hNGF demonstrated the feasibility o...

Biotech pharmaceuticals and biotherapy: an overview.

Broadly, the history of pharmaceutical biotechnology includes Alexander Fleming"s discovery of penicillin in a common mold, in 1928, and the subsequent development-prompted by World War II injuries-of large-scale manufacturing methods to grow the organism in tanks of broth. Pharmaceutical biotechnology has since changed enormously. Two breakthroughs of the late 1970s became the basis of the mod...

Biotechnology and genetic engineering in the new drug development. Part I. DNA technology and recombinant proteins.

Pharmaceutical biotechnology has a long tradition and is rooted in the last century, first exemplified by penicillin and streptomycin as low molecular weight biosynthetic compounds. Today, pharmaceutical biotechnology still has its fundamentals in fermentation and bioprocessing, but the paradigmatic change affected by biotechnology and pharmaceutical sciences has led to an updated definition. T...

Application of Recombinant DNA Technology (Genetically Modified Organisms) to the Advancement of Agriculture, Medicine, Bioremediation and Biotechnology Industries

Genetic engineering has always been a topic of controversy as the balance it aims to reach between the benefits accrued to humans and attendant ethical considerations is open to debate. In each of the diverse fields of agriculture, medicine, bioremediation and biotechnology concerns vary in a discipline-specific manner. However, the principal source of apprehension often involves the ecological...